Dolastatin 15 (Synonyms: NSC 617668) |
| Catalog No.GA21397 |
Dolabella auricularia에서 파생된 뎁시펩티드인 Dolastatin 15(DLS 15)는 구조적으로 항튜불린제 Dolastatin 10과 관련된 강력한 항유사분열제입니다. Dolastatin 15는 다발성 골수종 세포에서 세포 주기 정지 및 세포자멸사를 유도합니다. Dolastatin 15는 ADC 세포독소로 사용할 수 있습니다.
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Cas No.: 123884-00-4
Sample solution is provided at 25 µL, 10mM.
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Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic
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