>>H-Glu-Gly-Arg-chloromethylketone

H-Glu-Gly-Arg-chloromethylketone

Catalog No.GA22381

GGACK (EGR-CMK)는 u-플라스미노겐 활성화제의 억제제입니다. 인간 헵신의 불가역 공유결합 억제제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

H-Glu-Gly-Arg-chloromethylketone Chemical Structure

Cas No.: 65113-67-9

Size 가격 재고 수량
5mg
US$601.00
재고 있음
25mg
US$2,103.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description of H-Glu-Gly-Arg-chloromethylketone

GGACK (EGR-CMK), inhibitor of the u-plasminogen activator. Irreversible covalent inhibitor of human hepsin.

Chemical Properties of H-Glu-Gly-Arg-chloromethylketone

Cas No. 65113-67-9 SDF
Formula C14H25ClN6O5 M.Wt 392.84
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of H-Glu-Gly-Arg-chloromethylketone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.5456 mL 12.7278 mL 25.4557 mL
5 mM 0.5091 mL 2.5456 mL 5.0911 mL
10 mM 0.2546 mL 1.2728 mL 2.5456 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of H-Glu-Gly-Arg-chloromethylketone

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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