>>α-Dendrotoxin

α-Dendrotoxin

Catalog No.GA23990

α-Dendrotoxin (α-DTX), from the venom of the Eastern green mamba, Dendroaspis angusticeps, selectively blocks voltage-gated inactivating K? channels in synaptosomes.

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α-Dendrotoxin Chemical Structure

Cas No.: 74504-53-3

Size 가격 재고 수량
0.5mg
US$1,388.00
재고 있음
0.1mg
US$423.00
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1mg
US$2,246.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description of α-Dendrotoxin

α-Dendrotoxin (α-DTX), from the venom of the Eastern green mamba, Dendroaspis angusticeps, selectively blocks voltage-gated inactivating K channels in synaptosomes.

Chemical Properties of α-Dendrotoxin

Cas No. 74504-53-3 SDF
Formula C305H472N98O84S6 M.Wt 7048.11
Solubility 1 mg/mL in 10% acetic acid Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of α-Dendrotoxin

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.1419 mL 0.7094 mL 1.4188 mL
5 mM 0.0284 mL 0.1419 mL 0.2838 mL
10 mM 0.0142 mL 0.0709 mL 0.1419 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of α-Dendrotoxin

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for α-Dendrotoxin

Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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