GA3-AM |
| Catalog No.GC50158 |
GA3-AM은 식물 호르몬 지베렐린산의 세포 투과성 유사체로서 화학적 이량체화 또는 이량체화의 화학적 유도제 역할을 합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1373154-68-7
Sample solution is provided at 25 µL, 10mM.
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Gibberellin-analog (GA3) chemical dimerizer; induces rapid dimerization of GAIs and GID1. GA3-AM crosses the plasma membrane, is cleaved by cytosolic esterase releasing GA3, which then binds GID1- this complex then in turn forms a complex with GAI; this system works on a timescale of seconds (EC50 = 310 nM). GA3 and rapamycin chemically inducible dimerization systems are orthogonal. Cell permeable.
Lin et al (2013) Rapidly reversible manipulation of molecular activities using dual chemical dimerizers Angew.Chem.Int.Ed.Engl. 52 6450 PMID:23649661 |Miyamoto et al (2012) Rapid and orthogonal logic gating with a gibberellin-induced dimerization system Nat.Chem.Biol. 8 465 PMID:22446836
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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