Gastrofensin AN 5 free base |
| Catalog No.GC32051 |
4-페닐-테트라히드로이소퀴놀린 유도체인 Gastrofensin AN 5 유리 염기는 항궤양제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 89845-16-9
Sample solution is provided at 25 µL, 10mM.
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Gastrofensin AN 5 free base, a 4-phenyl-tetrahydroisoquinoline derivative, is an antiulcer agent.
Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1].
[1]. Ivanova N, et al. A new class of antiulcer drugs. I. Antiulcer effect of AN5, a 4-phenyl-tetrahydroisoquinoline derivative, on different experimental models of ulcer in rats. Methods Find Exp Clin Pharmacol. 1990 Jul-Aug;12(6):401-10.
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