Cucurbitacin IIa |
| Catalog No.GC35758 |
Cucurbitacin IIa는 Hemsleya amalils Diels에서 분리된 트리테르펜으로 암세포의 세포자살을 유도하고 서바이빈의 발현을 감소시키며 phospho-Histone H3를 감소시키고 암세포에서 절단된 PARP를 증가시킵니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58546-34-2
Sample solution is provided at 25 µL, 10mM.
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Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].
[1]. Boykin C, et al. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. Br J Cancer. 2011 Mar 1;104(5):781-9.
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