Dihydrexidine |
| Catalog No.GC35864 |
디하이드렉시딘(DAR-0100)은 D1 수용체에 대한 IC50이 10nM인 고강력, 선택적 및 완전한 효능 D1-유사 도파민 수용체(D1/D5) 작용제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 123039-93-0
Sample solution is provided at 25 µL, 10mM.
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Dihydrexidine (DAR-100) is a high potent, selective and full efficacy D1 dopamine receptor agonist with an IC50 of 10 nM, and displays some affinity for the D2 receptor. Dihydrexidine (DAR-100) exhibits potent antiparkinsonian activity[1][2][3]. IC50: 10 nM (D1 dopamine receptor)[1]
[1]. Lovenberg TW, et al. Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist. Eur J Pharmacol. 1989 Jul 4;166(1):111-3. [2]. Mottola DM, et al. Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. J Pharmacol Exp Ther. 1992 Jul;262(1):383-93. [3]. Salmi P,et al. Dihydrexidine--the first full dopamine D1 receptor agonist. CNS Drug Rev. 2004 Fall;10(3):230-42.
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