>>Peptides>>HER2/neu (654-662) GP2

HER2/neu (654-662) GP2

Catalog No.GC36219

HER2/neu(654-662) GP2는 인간 표피 성장 인자 수용체 2(HER2/nue, 654-662)에서 파생된 9개의 아미노산 펩타이드로 다양한 상피 세포에 반응하는 HLA-A2 제한 세포독성 T 림프구(CTL)를 유도합니다. 암.

Products are for research use only. Not for human use. We do not sell to patients.

HER2/neu (654-662) GP2 Chemical Structure

Cas No.: 160790-21-6

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Sample solution is provided at 25 µL, 10mM.

Description of HER2/neu (654-662) GP2

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654-662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

[1]. Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306. [2]. Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.

Chemical Properties of HER2/neu (654-662) GP2

Cas No. 160790-21-6 SDF
Formula C42H77N9O11 M.Wt 884.11
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of HER2/neu (654-662) GP2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.1311 mL 5.6554 mL 11.3108 mL
5 mM 0.2262 mL 1.1311 mL 2.2622 mL
10 mM 0.1131 mL 0.5655 mL 1.1311 mL
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In vivo Formulation Calculator (Clear solution) of HER2/neu (654-662) GP2

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for HER2/neu (654-662) GP2

Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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