>>Signaling Pathways>> JAK/STAT Signaling>> JAK>>JAK2-IN-4

JAK2-IN-4

Catalog No.GC36364

JAK2-IN-4(화합물 16h)는 JAK2 및 JAK3에 대해 IC50 값이 각각 0.7nM 및 23.2nM인 선택적 JAK2/JAK3 억제제입니다.

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JAK2-IN-4 Chemical Structure

Cas No.: 1438284-00-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1]. IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].

[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83.

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