LSD1-IN-5 |
Catalog No.GC36484 |
LSD1-IN-5(화합물 4e)는 121nM의 IC50을 갖는 라이신 특이적 데메틸라제 1(LSD1)의 강력하고 가역적인 억제제입니다. LSD1-IN-5는 히스톤 H3의 디메틸화된 Lys4를 증가시키고 LSD1의 발현에 영향을 미치지 않습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2035912-55-9
Sample solution is provided at 25 µL, 10mM.
LSD1-IN-5 (Compound 4e) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 121 nM (LSD1)[1]
[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
Average Rating: 5
(Based on Reviews and 20 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *