NSC16168 |
| Catalog No.GC36775 |
NSC16168은 IC50 값이 0.42μM인 ERCC1-XPF의 특정 억제제입니다. NSC16168은 DNA 복구를 억제하고 암에서 CDDP 효능을 강화합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6837-93-0
Sample solution is provided at 25 µL, 10mM.
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NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer[1]. IC50: 0.42 μM (ERCC1-XPF)[1].
[1]. Arora S, et al. Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells. Oncotarget. 2016 Nov 15;7(46):75104-75117.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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