THIP |
| Catalog No.GC37784 |
THIP(Gaboxadol)은 선택적 시냅스 외 GABAA 수용체(eGABAR) 작용제(혈액뇌장벽 투과성 포함)이며 δ-GABAAR에 대해 13μM의 EC50 값을 보여줍니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 64603-91-4
Sample solution is provided at 25 µL, 10mM.
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THIP (Gaboxadol) is a selective δ-aminobutyric acid type A receptor (δ-GABAAR) agonist, functionally selective GABAAR ligand, exhibits agonism at α4β1δ, α4β3δ and weak antagonism at αβγ and α4β2δ GABAARs[1]. α4β3δ GABAAR|13 μM (EC50)
[1]. Hoestgaard-Jensen K, et al. Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain. J Neurosci. 2014 Dec 3;34(49):16256-72.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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