Tiagabine hydrochloride hydrate |
| Catalog No.GC37788 |
티아가빈 염산염 수화물은 항경련제로 사용되는 강력하고 선택적인 GABA 흡수 억제제이며, 시냅토솜, 뉴런 및 신경교에서 각각 [3H]GABA 흡수에 대한 IC50이 67, 446 및 182nM입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 145821-57-4
Sample solution is provided at 25 µL, 10mM.
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Tiagabine hydrochloride hydrate is a potent and selective GABA uptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].
[1]. Braestrup C, et al. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier. J Neurochem. 1990 Feb;54(2):639-47.
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