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Tuberculosis inhibitor 1

Catalog No.GC37834

결핵 억제제 1은 EC50이 5nM인 강력하고 세포독성이 없는 트리파노소마 브루세이 성장 억제제입니다.

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Tuberculosis inhibitor 1 Chemical Structure

Cas No.: 2230810-28-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1]. EC50: 5 nM (Trypanosoma brucei)[1]

Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1].

[1]. Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692.

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