WKYMVM TFA |
| Catalog No.GC37936 |
WKYMVM(TFA)은 강력한 N-포르밀 펩티드 수용체(FPR1) 및 FPRL1/2 작용제이며 또한 화학주성, 보체 수용체-3의 동원 및 NADPH 산화효소의 활성화와 같은 여러 백혈구 효과기 기능을 활성화합니다. .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1313730-09-4
Sample solution is provided at 25 µL, 10mM.
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WKYMVM (TFA) is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase[1][2]. FPR1, FPRL1[1], FPRL2[2]
[1]. Christophe T, et al. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem. 2001 Jun 15;276(24):21585-93. [2]. Christophe T, et al. Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4. Scand J Immunol. 2002 Nov;56(5):470-6.
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