Zaurategrast ethyl ester sulfate |
| Catalog No.GC37962 |
CT7758의 에틸 에스테르 전구약물인 Zaurategrast 에틸 에스테르 설페이트(CDP323 설페이트)는 염증 및 자가면역 질환의 치료에 사용되는 α4β1/α4β7 인테그린 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1214261-78-5
Sample solution is provided at 25 µL, 10mM.
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Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. α4β1/α4β7 integrin[1]
Zaurategrast ethyl ester sulfate (CDP323 sulfate), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].
[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. [2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases• Drug Discov Today. 2007 Jul;12(13-14):569-76.
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