Barbadin |
| Catalog No.GC38351 |
Barbadin은 새롭고 선택적인 β-arrestin/β2-adaptin 상호작용 억제제로서 β-arrestin1의 경우 19.1μM, β-arrestin2의 경우 15.6μM의 IC50 값을 가지고 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 356568-70-2
Sample solution is provided at 25 µL, 10mM.
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Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors[1].
[1]. Beautrait A, et al. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nat Commun. 2017 Apr 18;8:15054. doi: 10.1038/ncomms15054.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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