>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> Drug-Linker Conjugates for ADC>>SPP-DM1

SPP-DM1

Catalog No.GC38478

SPP-DM1은 ADC 링커 SPP를 통해 연결된 DM1(강력한 미세소관 교란제)을 사용하여 강력한 항종양 활성을 갖는 ADC용 약물-링커 접합체입니다.

Products are for research use only. Not for human use. We do not sell to patients.

SPP-DM1 Chemical Structure

Cas No.: 452072-20-7

Size 가격 재고 수량
1mg
US$517.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPP-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].

[1]. Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.

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Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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