>>Signaling Pathways>> Neuroscience>> 5-HT Receptor>>Geissoschizine methyl ether

Geissoschizine methyl ether

Catalog No.GC38529

운카리아 후크에서 발견되는 주요 인돌 알칼로이드인 Geissoschizine methyl ether는 향정신성 효과가 있는 Yokukansan의 주요 활성 성분입니다.

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Geissoschizine methyl ether Chemical Structure

Cas No.: 60314-89-8

Size 가격 재고 수량
1mg
US$174.00
재고 있음
5mg
US$524.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist[1][2].

[1]. Matsumoto T, et al. In vitro identification of human cytochrome P450 isoforms involved in the metabolism of Geissoschizine methyl ether, an active component of the traditional Japanese medicine Yokukansan. Xenobiotica. 2016;46(4):325-34. [2]. Nishi A, et al. Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ?A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan. Neuroscience. 2012 Apr 5;207:124-36.

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