Gemcitabine-O-Si(di-iso)-O-Mc |
| Catalog No.GC60870 |
Gemcitabine-O-Si(di-iso)-O-Mc는 ADC 링커를 통해 연결된 Gemcitabine(피리미딘 뉴클레오시드 유사체 및 항종양제)을 사용하여 강력한 항종양 활성을 갖는 ADC용 약물-링커 접합체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Gemcitabine-O-Si(di-iso)-O-Mc is a drug-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent;), linked via the ADC linker[1].
Antibody drug conjugates (ADC) couple therapeutic monoclonal antibodies (mAb) with potent toxins through a linker that is stable within systemic circulation, but cleaves within the target cells[1].
[1]. Mathew C. Finniss, et al. A versatile acid-labile linker for antibody-drug conjugate. MedChemComm, Issue 9, 2014.
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