Chlorahololide C (Synonyms: Chlorahololide C) |
Catalog No.GF15396 |
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Cas No.: 1007859-25-7
Sample solution is provided at 25 µL, 10mM.
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 渭M.
Chlorahololide C (0.1-100 渭M) inhibits the delayed rectifier K+ current (IK) in rat dissociated hippocampal neurons, with an IC50 of 3.6 渭M[1].
[1]. Yang SP, et, al. Chlorahololides C-F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius. Tetrahedron. 2008 Feb; 64(9):2027-2034.
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