>>Signaling Pathways>> Obesity, Appetite Control & Diabetes>> Obesity>>Ghrelin (rat) (palmitoyl) (trifluoroacetate salt)

Ghrelin (rat) (palmitoyl) (trifluoroacetate salt)

Catalog No.GC43753

Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).

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Ghrelin (rat) (palmitoyl) (trifluoroacetate salt) Chemical Structure

Size 가격 재고 수량
500μg
US$324.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). Ghrelin requires an n-octanoyl modification at serine 3 for binding to GHS-R. Ghrelin (rat) (palmitoyl) is a palmitoylated form of ghrelin. Palmitoylated ghrelin is an agonist of GHS-R with a similar potency as octanoyl-ghrelin in HEK293 cells expressing human GHS-R1a (IC50 = 0.87 nM; EC50 = 8.3 nM for increasing calcium accumulation). In mice, palmitoylated ghrelin (0.9 nmol, i.c.v.) increases food intake after 24 hours but not at shorter timepoints of two and four hours. It also increases fat mass without effects on locomotor activity or energy expenditure.

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