Gln-AMS TFA |
| Catalog No.GC34331 |
Gln-AMS(TFA)는 Ia형 아미노아실-tRNA 합성효소(AARS) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM.
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor[2].
[1]. Rath VL, et al. How glutaminyl-tRNA synthetase selects glutamine. Structure. 1998 Apr 15;6(4):439-49. [2]. Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.
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