GSK2945 hydrochloride |
| Catalog No.GC39168 |
GSK2945 염산염은 3차 아민 계열이며 EC50이 각각 21.5μM 및 20.8μM인 매우 특이적인 Rev-erbα/REV-ERBα(마우스/인간 역적혈구증가증 바이러스 α) 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism[1].
[1]. Zhang T, et al. REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1. Drug Metab Dispos. 2018 Mar;46(3):248-258.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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