>>Signaling Pathways>> Tyrosine Kinase>> Src>>GW297361

GW297361

Catalog No.GC71250

GW297361는 옥신돌 CDK 억제제로 세포에서 pho85-선택적 반응을 이끌어낸다.

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GW297361 Chemical Structure

Cas No.: 388627-21-2

Size 가격 재고 수량
1 mg
US$306.00
재고 있음
5 mg
US$765.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively.

GW297361 (20 μM; 15 min) partially inhibits Cdk1 within cells[1].

References:
[1]. Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407.

리뷰

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