HDAC3 Inhibitor (Synonyms: Histone Deacetylase 3) |
| Catalog No.GC41495 |
HDAC3 억제제(화합물 5)는 IC50이 5.96nM인 강력하고 선택적인 HDAC3 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2044701-99-5
Sample solution is provided at 25 µL, 10mM.
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HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In addition, it is selective for acute myeloid, monocytic, and lymphoblastic leukemia cell lines (EC50s = 36.37, 76.64, and 151.7 nM, respectively) over chronic myeloid, acute promyelocytic, and acute lymphoblastic cells (EC50s = 2,160, >10,000, and >10,000 nM, respectively).
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
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