>>Signaling Pathways>> Neuroscience>> Monoamine Oxidase>>hMAO-B-IN-4

hMAO-B-IN-4

Catalog No.GC69234

hMAO-B-IN-4 (화합물 B10)은 선택적이고 가역적이며 혈청뇌장벽(BBB)을 통과할 수 있는 인간 단일아민산화효소-B(hMAO-B) 억제제로, IC50 값과 Ki 값은 각각 0.067 및 0.03 μM입니다. hMAO-B-IN-4는 hMAO-A를 억제하는 IC50 값이 33.82 μM입니다. hMAO-B-IN-4는 알츠하이머병과 파킨슨병 연구에 사용될 수 있습니다.

Products are for research use only. Not for human use. We do not sell to patients.

hMAO-B-IN-4 Chemical Structure

Cas No.: 1666119-75-0

Size 가격 재고 수량
10mg
US$117.00
재고 있음
25mg
US$225.00
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50mg
US$360.00
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100mg
US$585.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of hMAO-B-IN-4

Cas No. 1666119-75-0 SDF
Formula C20H16O2S M.Wt 320.4
Solubility DMSO : 50 mg/mL (156.05 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of hMAO-B-IN-4

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.1211 mL 15.6055 mL 31.211 mL
5 mM 0.6242 mL 3.1211 mL 6.2422 mL
10 mM 0.3121 mL 1.5605 mL 3.1211 mL
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In vivo Formulation Calculator (Clear solution) of hMAO-B-IN-4

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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