Hydroxychloroquine |
| Catalog No.GC62055 |
하이드록시클로로퀸은 Toll 유사 수용체 7/9(TLR7/9) 신호 전달을 억제할 수도 있는 합성 항말라리아제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 118-42-3
Sample solution is provided at 25 µL, 10mM.
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Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].
[1]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.
[2]. Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.
[3]. Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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