IMPDH2-IN-2 |
| Catalog No.GC70917 |
IMPDH2-IN-2은 강력 한 억제의 inosine 5'-monophosphate dehydrogenase (IMPDH) 기성, 앱 14 μ M의 가치, 각각이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1434517-02-8
Sample solution is provided at 25 µL, 10mM.
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IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent.
References:
[1]. Chacko S, et al. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents [published correction appears in J Med Chem. 2021 Dec 23;64(24):18233-18234]. J Med Chem. 2018;61(11):4739-4756.
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