Isoprocurcumenol |
| Catalog No.GC70377 |
Isoprocurcumenol은 구아인 형태의 세스키테르펜으로, 쿠르쿠마코모사에서 분리될 수 있다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 102130-90-5
Sample solution is provided at 25 µL, 10mM.
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Isoprocurcumenol (10 μM, 0-1 h) increases the phosphorylation of ERK and AKT[3].
Isoprocurcumenol (0-200 μM, 24 or 48 h) induces the proliferation of keratinocytes HaCaT cells[3].
Isoprocurcumenol (1 μM, 1 h) increases the expression of genes related to cell growth and proliferation, such as c-fos, c-jun, c-myc, and egr-1, through activation of the EGFR signaling pathway[3].
Isoprocurcumenol induces cell recovery and wound healing[3].
References:
[1]. Qu Y, et al. Sesquiterpenes from Curcuma comosa. J Nat Med. 2009 Jan;63(1):102-4.
[2]. Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414.
[3]. Kwon PK, et al. Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation. Int J Mol Sci. 2021 Nov 22;22(22):12579.
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