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ISX 9 (Synonyms: Isoxazole 9, Neuronal Differentiation Inducer III)

Catalog No.GC10472

ISX 9(Isoxazole 9)는 성체 신경 줄기 세포 분화의 강력한 유도제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

ISX 9 Chemical Structure

Cas No.: 832115-62-5

Size 가격 재고 수량
10mg
US$102.00
재고 있음
50mg
US$232.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.

References:
[1]. Petrik D, et al. Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule. FASEB J. 2012 Aug;26(8):3148-3162.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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