IZ-Chol (Synonyms: IZ-Cholesterol) |
| Catalog No.GC91558 |
IZ-Chol is an ionizable cationic lipid (pKas = 7.29 and 3.96) containing cholesterol .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 191990-35-9
Sample solution is provided at 25 µL, 10mM.
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IZ-Chol is an ionizable cationic lipid (pKas = 7.29 and 3.96) containing cholesterol .[1] LNPs containing IZ-chol can be complexed with DNA, with the plasmid-binding efficacy dependent, in part, on the type of helper lipids in the LNP formulation.
References:
[1].Wang, Y., Jiang, J., Ding, Z., et al.Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivativesJ. Liposome Res.(2024).
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