JAK1-IN-4 |
| Catalog No.GC33258 |
JAK1-IN-4는 JAK1, JAK2 및 JAK3에 대해 IC50이 각각 85nM, 12.8μM 및 >30μM인 강력하고 선택적인 JAK1 억제제입니다. JAK1-IN-4는 NCI-H 1975 세포(IC50, 227nM)에서 STAT3 인산화를 억제합니다.
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Cas No.: 2091134-35-7
Sample solution is provided at 25 µL, 10mM.
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JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1].
[1]. Annika Birgitta Margareta ?STRAND, et al. Compounds and methods for inhibiting jak.
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