JNJ-49095397 |
| Catalog No.GC70499 |
JNJ-49095397 (RV568) 는 p38 MAPK α 및 감마 아형에 대한 흡입성 좁은 스펙트럼 효소 억제제 (NSKI)입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1220626-82-3
Sample solution is provided at 25 µL, 10mM.
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JNJ-49095397 (RV568) (1 pg-1 μg/mL; 4 h) inhibits LPS-induced CXCL8 release in PBMCs and d-U937 cells[1].
JNJ-49095397 (1 μg-1 g/mL; 4 h) inhibits TNFα-induced interleukin (IL)-6 and CXCL8 release in a concentration-dependent manner[1].
JNJ-49095397 (RV568) (1-20 μg/mouse; intratracheal; once) shows anti-inflammatory activities in LPS-induced neutrophil accumulation mouse model[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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