JNK-IN-11 |
Catalog No.GC71114 |
JNK-IN-11 (화합물 1) 는 JNK 억제제의 강력하며 JNK1, JNK2, JNK3에 대한 IC50 값은 각각 2.2, 21.4, 1.8 µM입니다.
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Cas No.: 676594-38-0
Sample solution is provided at 25 µL, 10mM.
JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease.
References:
[1]. Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.
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