Kahweol |
| Catalog No.GC40573 |
Kahweol is a natural diterpene that is isolated from coffee beans.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6894-43-5
Sample solution is provided at 25 µL, 10mM.
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Kahweol is a natural diterpene that is isolated from coffee beans. It increases glutathione S-transferase activity in the gut mucosa of mice and, with the diterpene cafestol, induces glutathione S-transferase expression in rat livers. Kahweol has anti-inflammatory effects in RAW macrophages, inhibiting LPS-induced nitric oxide and prostaglandin E2 production (IC50 = 54 and 23 μM, respectively). Kahweol also is antiangiogenic, blocking the proliferation of endothelial cells (IC50 = 50 μM) and inhibiting endothelial migration, invasion, and tube formation. Kahweol is easily oxidized in the presence of air.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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