L-Carnitine-d9 |
| Catalog No.GC71651 |
L-Carnitine-d9는 l-카르니틴으로 표기된 중수소이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 126827-79-0
Sample solution is provided at 25 µL, 10mM.
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Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017;42(6):1661-1675.
[3]. Miyagawa T, et al. Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. PLoS One. 2013;8(1):e53707.
[4]. Abd Eldaim MA, et al. l-Carnitine-induced amelioration of HFD-induced hepatic dysfunction is accompanied by a reduction in hepatic TNF-α and TGF-β1. Biochem Cell Biol. 2018;96(6):713-725.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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