L-erythro Sphingosine (d18:1) (Synonyms: L-erythro Sphingosine, L-erythro-C18-Sphingosine) |
| Catalog No.GC40770 |
L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6036-75-5
Sample solution is provided at 25 µL, 10mM.
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L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1) . It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%) and superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils as well as reduces growth of CHO cells (IC50s = 1.3 and 2 μM, respectively). L-erythro Sphingosine also inhibits dephosphorylation of the tumor suppressor retinoblastoma gene product (pRb; EC50 = 5 μM) and growth of MOLT-4 acute lymphoblastic leukemia cells (IC50 = 3.7 μM).
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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