>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>Lathosterol

Lathosterol (Synonyms: Δ7-Cholestenol, γ-Cholestenol)

Catalog No.GC18289

라토스테롤은 콜레스테롤과 같은 분자입니다.

Products are for research use only. Not for human use. We do not sell to patients.

Lathosterol Chemical Structure

Cas No.: 80-99-9

Size 가격 재고 수량
10mg
US$44.00
재고 있음
25mg
US$102.00
재고 있음
50mg
US$195.00
재고 있음
100mg
US$340.00
재고 있음

Tel:(909) 407-4943 Email: sales@glpbio.com


고객 리뷰

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description of Lathosterol

Lathosterol is an intermediate in the biosynthesis of cholesterol. Serum levels of lathosterol correlate with cholesterol synthesis and have been used as biomarkers of excess cholesterol production. Lathosterol accumulates in lathosterolosis, a disorder characterized by a deficiency of lathosterol 5-desaturase, the enzyme that converts lathosterol to 7-dehydro cholesterol .

Chemical Properties of Lathosterol

Cas No. 80-99-9 SDF
Synonyms Δ7-Cholestenol, γ-Cholestenol
Chemical Name 5α-cholest-7-en-3β-ol
Canonical SMILES CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Formula C27H46O M.Wt 386.7
Solubility DMF: 2 mg/ml,DMSO: 0.1 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Lathosterol

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.586 mL 12.9299 mL 25.8598 mL
5 mM 0.5172 mL 2.586 mL 5.172 mL
10 mM 0.2586 mL 1.293 mL 2.586 mL
  • Molarity Calculator

  • Dilution Calculator

  • Molecular Weight Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of Lathosterol

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

리뷰

Review for Lathosterol

Average Rating: 5 ★★★★★ (Based on Reviews and 16 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for Lathosterol

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.