Lenalidomide-acetylene-C5-COOH (Synonyms: Cereblon ligand-linker Conjugate) |
| Catalog No.GC60983 |
레날리도마이드-아세틸렌-C5-COOH(화합물 43; 세레블론 리간드-링커 접합체)는 CRBN 단백질 모집에 사용되는 레날리도마이드 기반 세레블론 리간드입니다. 레날리도마이드-아세틸렌-C5-COOH는 링커에 의해 단백질에 대한 리간드에 연결되어 PROTAC을 형성할 수 있습니다.
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Cas No.: 2429878-72-6
Sample solution is provided at 25 µL, 10mM.
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Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1].
[1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
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