γ-Linolenic Acid ethyl ester (Synonyms: GLA ethyl ester) |
| Catalog No.GC40787 |
리놀렌산 에틸 에스테르(에틸 γ-리놀레네이트)는 류코트리엔 B4 수용체 4(LTB4) 길항제입니다.
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Cas No.: 31450-14-3
Sample solution is provided at 25 µL, 10mM.
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α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation. Linolenic acid ethyl ester (LAEE) is a neutral, more lipophilic form of the free acid that can be used as an exogenous source of α-linolenic acid. This ethanol metabolite may contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells (HSC). LAEE increases cyclin E expression and Cdk2 activity as well as increases ERK and JNK activity.
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