Loviride (R 89439) |
| Catalog No.GC32358 |
Loviride(R 89439)(R 89439)는 비뉴클레오사이드 역전사효소 억제제(NNRTI)로, IC50이 0.3 μM인 HIV-1의 역전사효소입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 147362-57-0
Sample solution is provided at 25 µL, 10mM.
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Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with IC50s of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1].
Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1].
[1]. Witvrouw M, et al. Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV. AIDS. 1999 Aug 20;13(12):1477-83.
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