Lupeol acetate |
Catalog No.GC60231 |
Lupeol의 유도체인 Lupeol acetate는 TNF-α, IL-1β, MCP-1, COX-2, VEGF 및 granzyme B의 하향 조절을 통해 대식세포의 활성화와 파골세포 형성을 억제하여 류마티스 관절염(RA)의 진행을 억제합니다[1 ].
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Cas No.: 1617-68-1
Sample solution is provided at 25 µL, 10mM.
Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].
[1]. Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.
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