m-PEG10-azide |
| Catalog No.GC67319 |
m-PEG10-azide PEG 기반 PROTAC 링커는 PROTAC의 합성에 사용될 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 2112738-12-0
Sample solution is provided at 25 µL, 10mM.
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m-PEG10-azide a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.
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