Mca-VDQVDGW-K(Dnp)-NH2 (acetate) (Synonyms: Caspase-7 Fluorogenic Substrate I,Mca-VDQVDGW-Lys(Dnp)-NH2) |
| Catalog No.GC91841 |
Mca-VDQVDGW-K(Dnp)-NH2 is a substrate for caspase-7.
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Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Mca-VDQVDGW-K(Dnp)-NH2 is a substrate for caspase-7.[1] Upon cleavage by caspase-7, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify caspase-7 activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
References:
[1].Yu, M.-S., Suen, K.-C., Kwok, N.-S., et al.Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responsesApoptosis11(5)687-700(2006).
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