MRS 1754 |
| Catalog No.GC13807 |
MRS 1754는 인간과 쥐 모두의 A1 및 A3 수용체에 대해 매우 낮은 친화성을 갖는 A2B 아데노신 수용체에 대한 선택적 길항제 방사성 리간드입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 264622-58-4
Sample solution is provided at 25 µL, 10mM.
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MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats[1].
The most potent displacer of [3H]MRS 1754 binding is MRS 1754. The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM[1].
References:
[1]. Ji X, et al. [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. Biochem Pharmacol. 2001 Mar 15;61(6):657-63.
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