MRZ 2-514 |
| Catalog No.GC31036 |
MRZ 2-514는 NMDA 수용체(글리신B)의 스트리크닌-민감성 조절 부위의 길항제이며 Ki는 33μM입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 202808-11-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
MRZ 2-514 has IC50 values against peak AMPA-induced currents of 72.7 μM[1].
MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid[1].
[1]. Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283(3), 1264-1275
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *