Mulberrin (Kuwanon C) (Synonyms: Mulberrin) |
Catalog No.GC32597 |
Mulberrin(Kuwanon C)은 1.8±1.5 &9586;888의 IC50 값을 갖는 유기 음이온 수송 폴리펩타이드 2B1(OATP2B1) 매개 에스트론-3-설페이트(E3S) 흡수의 강력한 억제제입니다.
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Cas No.: 62949-79-5
Sample solution is provided at 25 µL, 10mM.
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
Mulberrin is a flavone with two isopentenyl groups at positions 3 and 8. Mulberrin is a strong inhibitor of OATP2B1 with more than 80% inhibition.Mulberrin also inhibits organic anion-transporting polypeptide (OATP)-mediated uptake of Atorvastatin, Fluvastatin, and Rosuvastatin[1].
[1]. Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54(2):293-302.
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