>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> ADC Linker>>N3-PEG3-C2-PFP ester

N3-PEG3-C2-PFP ester

Catalog No.GC66829

N3-PEG3-C2-PFP 에스테르는 항체-약물 접합체(ADC)의 합성에 사용되는 절단 불가능한 3단위 PEG 링커입니다.821d96072c2d58d8970e76f526b0f6b8

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N3-PEG3-C2-PFP ester Chemical Structure

Cas No.: 1807530-07-9

Size 가격 재고 수량
100mg
US$1,387.00
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500mg
US$4,162.00
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Sample solution is provided at 25 µL, 10mM.

Description of N3-PEG3-C2-PFP ester

N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

Chemical Properties of N3-PEG3-C2-PFP ester

Cas No. 1807530-07-9 SDF
Formula C15H16F5N3O5 M.Wt 413.3
Solubility Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of N3-PEG3-C2-PFP ester

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4195 mL 12.0977 mL 24.1955 mL
5 mM 0.4839 mL 2.4195 mL 4.8391 mL
10 mM 0.242 mL 1.2098 mL 2.4195 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of N3-PEG3-C2-PFP ester

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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