Nedosiran sodium |
| Catalog No.GC70681 |
Nedosiran sodium는 간 lactate dehydrogenase (LDH) 효소의 생성을 억제하도록 설계된 GalNAc-dsRNA conjugate이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2247026-22-6
Sample solution is provided at 25 µL, 10mM.
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References:
[1]. Kevin Shee, et al. Nedosiran Dramatically Reduces Serum Oxalate in Dialysis-Dependent Primary Hyperoxaluria 1: A Compassionate Use Case Report. Urology.2021 Oct;156:e147-e149.
[2]. Gema Ariceta, et al. Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria. Kidney Int Rep.2021 Feb 3;6(4):1088-1098.
[3]. Thomas A Forbes, et al. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria. Br J Clin Pharmacol.2021 May 22.
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